Thursday, June 11, 2009

Muscle research and ME/CFS

NOTE: A new research study adds further support to the view that muscle tissue abnormalities play a role in the pathogenesis of ME/CFS - see abstract below.

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3 comments:

  1. does that explain the pain Dr Speedy?



    The MEA are featured on tomorrow's UK Sky news, Sat June 13th:

    ME/CFS research on Sky TV
    For reposting..



    From Dr Charles Shepherd



    The ME Association has been working with Sky TV news this week, who will be
    covering the subject of biomedical research into ME/CFS, the role of the
    MRC, and the gene expression studies.

    This item is designed is to link in with the European scientific meeting
    taking place in Norway on Saturday 13 June.



    We do not, at present, have details for times of this coverage but the item
    is likely to be included in news bulletins from mid morning onwards.



    Further information will follow.



    http://www.meassociation.org.uk/content/view/888/161/

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  2. Fatigue is generally subjective, but muscle function can be measured objectively.

    This from the BBC Science & Nature website:


    Slow twitch muscle fibres are good for endurance activities like long distance running or cycling. They can work for a long time without getting tired. Fast twitch muscles are good for rapid movements like jumping to catch a ball or sprinting for the bus. They contract quickly, but get tired fast, as they consume lots of energy.

    Most of your muscles are made up of a mixture of both slow and fast twitch muscle fibres. But, your soleus muscle in your lower leg and muscles in your back involved in maintaining posture contain mainly slow twitch muscle fibres. And muscles that move your eyes are made up of fast twitch muscle fibres.

    Chickens have fast and slow twitch muscle, too. Dark meat, like in chicken legs, is mainly made up of slow twitch fibres. White meat, like in chicken wings and breasts, is largely made up of fast twitch muscle fibres. Chickens use their legs for walking and standing, which they do most of the time. This doesn't use much energy. They use their wings for brief bursts of flight. This requires lots of energy and the muscles involved tire very quickly.

    Slow twitch and fast twitch muscle fibres make energy in different ways
    Muscles that contain a lot of slow twitch fibres are red, because they contain lots of blood vessels. Slow twitch muscle fibres rely on a rich supply of oxygenated blood as they use oxygen to produce energy for muscle contraction.

    Fast twitch muscle fibres don't use oxygen to make energy, so they don't need such a rich blood supply. This is why fast twitch muscles are lighter in colour than muscles that contain a lot of slow twitch muscle fibres.

    Fast twitch muscle fibres can produce small amounts of energy very quickly whereas slow twitch muscles can produce large amounts of energy slowly.

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  3. http://www.youtube.com/watch?v=i1YZJ72Lpcg

    Charles Shepherd interview, Sky news 13th June 09.

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