Research shows widespread inflammation and multisystemic neuropathology in Myalgic Encephalomyelitis (ME)

ProHealth.com
by International Consensus Panel
July 21, 2011

[Note: This definition of ME was produced by an International Consensus Panel of expert clinicians and researchers: Bruce M Carruthers MD, CM, FRCP(C), Marjorie I van de Sande BEd, Kenny L De Meirleir MD, PhD, Nancy G Klimas MD, Gordon Broderick PhD, Terry Mitchell MA, MD, FRCPath, Don Staines MBBS, MPH, FAFPHM, FAFOEM, AC Peter Powles MRACP, FRACP, FRCP(C), ABSM, Nigel Speight MA, MB, BChir, FRCP, FRCPCH, DCH, Rosamund Vallings MNZM, MB, BS, MRCS, LRCP, Lucinda Bateman MS, MD, Barbara Baumgarten- Austrheim MD, David S Bell MD, FAAP, Nicoletta Carlo- Stella MD, PhD, John Chia MD, Austin Darragh MA, MD, FFSEM. (RCPI, RCSI), FRSHFI Biol I (Hon), Daehyun Jo MD, PhD, Don Lewis MD, Alan R Light PhD, Sonya Marshall- Gradisbik PhD, Ismael Mena MD, Judy A Mikovits PhD, Kunihisa Miwa MD, PhD, Modra Murovska MD, PhD, Martin L Pall PhD, Staci Stevens MA.]

The label 'chronic fatigue syndrome' (CFS) has persisted for many years because of lack of knowledge of the etiological agents and of the disease process.

In view of more recent research and clinical experience that strongly point to widespread inflammation and multisystemic neuropathology, it is more appropriate and correct to use the term 'myalgic encephalomyelitis' (ME) because it indicates an underlying pathophysiology.

It is also consistent with the neurological classification of ME in the World Health Organization's International Classification of Diseases (ICD G93.3).

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