(Psychiatrist Peter White is Chief Medical Officer of the insurance company Swiss Re.)
------------------------------
Subject: Re: RES: Risk markers for both chronic fatigue and irritable bowel syndromes: a prospective case-control study in primary care
"Two subgroups of fatigue syndrome cases were studied: those with a diagnostic label that included the word 'post-viral' or 'post-infectious', which we call PVFS here, and the remainder, composed of CFS or ME, which we call CFS/ME."
Risk markers for both chronic fatigue and irritable bowel syndromes: a prospective case-control study in primary care.
Journal: Psychol Med. 2009 Apr 15:1-9. [Epub ahead of print]
Authors: Hamilton WT, Gallagher AM, Thomas JM, White PD.
Affiliation: Academic Unit of Primary Health Care, University of Bristol, Bristol, UK.
NLM Citation: PMID: 19366500
BACKGROUND: Fatigue syndromes and irritable bowel syndrome (IBS) often occur together. Explanations include being different manifestations of the same condition and simply sharing some symptoms.
Method: A matched case-control study in UK primary care, using data collected prospectively in the General Practice Research Database (GPRD). The main outcome measures were: health-care utilization, specific symptoms and diagnoses. Risk markers were divided into distant (from 3 years to 1 year before diagnosis) and recent (1 year before diagnosis).
RESULTS: A total of 4388 patients with any fatigue syndrome were matched to two groups of patients: those attending for IBS and those attending for another reason. Infections were specific risk markers for both syndromes, with viral infections being a risk marker for a fatigue syndrome [odds ratios (ORs) 2.3-6.3], with a higher risk closer to onset, and gastroenteritis a risk for IBS (OR 1.47, compared to a fatigue syndrome). Chronic fatigue syndrome (CFS) shared more distant risk markers with IBS than other fatigue syndromes, particularly other symptom-based disorders (OR 3.8) and depressive disorders (OR 2.3), but depressive disorders were a greater risk for CFS than IBS (OR 2.4). Viral infections were more of a recent risk marker for CFS compared to IBS (OR 2.8), with gastroenteritis a greater risk for IBS (OR 2.4).
CONCLUSIONS: Both fatigue and irritable bowel syndromes share predisposing risk markers, but triggering risk markers differ. Fatigue syndromes are heterogeneous, with CFS sharing predisposing risks with IBS, suggesting a common predisposing pathophysiology.
----------------------------------------
and here's the WHO definition of M.E., which they classified as a neurological illness since 1969:
M.E. ME/CFS is an acquired organic, pathophysiological, multi-systemic illness that occurs in both sporadic and epidemic forms. Myalgic Encephalomyelitis (ICD 10 G93.3), which includes CFS, is classified as a neurological disease in the World Health Organization's International Classification of Diseases (ICD). Chronic fatigue must not be confused with ME/CFS because the "fatigue" of ME/CFS represents pathophysiological exhaustion and is only one of many symptoms.
Prof White doesn't seem to be studying the same illness.
First half you've seen, Second half is Action for M.E.'s Nadia Conway.
http://www.youtube.com/watch?v=42nSNLQsVNs
I hope no-one believes that AfME are actually funding biomedical research; they are allegedly funding a project designed to have ME reclassified from a neurological illness to a mental one.
ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) is a physical disease. It is not a product of the patients’ imagination and is not a psychological problem. Funds have been used for research into the hypothetical psychiatric nature of the disease at the expense of biomedical research. Future research needs to be interdisciplinary and focused on the causes, early diagnosis and treatment of ME/CFS.
The British National Health Service has published NICE guidelines for this disorder which, according to ESME, are not helpful and might even induce relapse in some cases.
ESME will encourage research leading to the accumulation of new knowledge and to a better understanding of the disease, and will endeavour to raise funding for biomedical research in, and education about, ME/CFS.
4 comments:
Wonderful Dr Speedy - December is a cracker!
A weird & unscientific way to define M.E.?
(Psychiatrist Peter White is Chief Medical Officer of the insurance company Swiss Re.)
------------------------------
Subject: Re: RES: Risk markers for both chronic fatigue and irritable bowel syndromes: a prospective case-control study in primary care
"Two subgroups of fatigue syndrome cases were studied: those with a
diagnostic
label that included the word 'post-viral' or 'post-infectious', which we
call
PVFS here, and the remainder, composed of CFS or ME, which we call CFS/ME."
Risk markers for both chronic fatigue and irritable bowel syndromes:
a prospective case-control study in primary care.
Journal: Psychol Med. 2009 Apr 15:1-9. [Epub ahead of print]
Authors: Hamilton WT, Gallagher AM, Thomas JM, White PD.
Affiliation: Academic Unit of Primary Health Care, University of
Bristol, Bristol, UK.
NLM Citation: PMID: 19366500
BACKGROUND: Fatigue syndromes and irritable bowel syndrome (IBS)
often occur together. Explanations include being different
manifestations of the same condition and simply sharing some symptoms.
Method: A matched case-control study in UK primary care, using data
collected prospectively in the General Practice Research Database
(GPRD). The main outcome measures were: health-care utilization,
specific symptoms and diagnoses. Risk markers were divided into
distant (from 3 years to 1 year before diagnosis) and recent (1 year
before diagnosis).
RESULTS: A total of 4388 patients with any fatigue syndrome were
matched to two groups of patients: those attending for IBS and those
attending for another reason. Infections were specific risk markers
for both syndromes, with viral infections being a risk marker for a
fatigue syndrome [odds ratios (ORs) 2.3-6.3], with a higher risk
closer to onset, and gastroenteritis a risk for IBS (OR 1.47,
compared to a fatigue syndrome). Chronic fatigue syndrome (CFS)
shared more distant risk markers with IBS than other fatigue
syndromes, particularly other symptom-based disorders (OR 3.8) and
depressive disorders (OR 2.3), but depressive disorders were a
greater risk for CFS than IBS (OR 2.4). Viral infections were more of
a recent risk marker for CFS compared to IBS (OR 2.8), with
gastroenteritis a greater risk for IBS (OR 2.4).
CONCLUSIONS: Both fatigue and irritable bowel syndromes share
predisposing risk markers, but triggering risk markers differ.
Fatigue syndromes are heterogeneous, with CFS sharing predisposing
risks with IBS, suggesting a common predisposing pathophysiology.
----------------------------------------
and here's the WHO definition of M.E., which they classified as a neurological illness since 1969:
M.E.
ME/CFS is an acquired organic, pathophysiological, multi-systemic illness that occurs in both sporadic and epidemic forms. Myalgic Encephalomyelitis (ICD 10 G93.3), which includes CFS, is classified as a neurological disease in the World Health Organization's International Classification of Diseases (ICD). Chronic fatigue must not be confused with ME/CFS because the "fatigue" of ME/CFS represents pathophysiological exhaustion and is only one of many symptoms.
Prof White doesn't seem to be studying the same illness.
ME on Sky news again:
First half you've seen, Second half is Action for M.E.'s Nadia Conway.
http://www.youtube.com/watch?v=42nSNLQsVNs
I hope no-one believes that AfME are actually funding biomedical research; they are allegedly funding a project designed to have ME reclassified from a neurological illness to a mental one.
STATEMENT FROM ESME – EUROPEAN SOCIETY FOR ME
More Biomedical Research Needed
ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) is a physical
disease. It is not a product of the patients’ imagination and is not a
psychological problem. Funds have been used for research into the
hypothetical psychiatric nature of the disease at the expense of biomedical
research. Future research needs to be interdisciplinary and focused on the
causes, early diagnosis and treatment of ME/CFS.
The British National Health Service has published NICE guidelines for this
disorder which, according to ESME, are not helpful and might even induce
relapse in some cases.
ESME will encourage research leading to the accumulation of new knowledge
and to a better understanding of the disease, and will endeavour to raise
funding for biomedical research in, and education about, ME/CFS.
Stavanger, Norway, June 13, 2009
Launch Meeting ESME
PD Dr. Liv Bode
Prof. Dr. Med. Kenny De Meirleir
Dr. Med. Derek Enlander
Dr. Med. Ana Garcia Quintana
Prof. Dr. Hanns Ludwig
Prof. Dr. Med. Mária J. Molnár
Prof. Dr. Bodil Norrild
Prof. Dr. Med. Ola Didrik Saugstad
Prof. Dr. Med. Babill Stray-Pedersen
Prof. Dr. Med. Umberto Tirelli
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