Monday, June 29, 2009

Charcot's Bad Idea



Author: Simon Overton
ISBN: 1409265420

Angela Kennedy:
"This book charts the ways in which the ideas of a 19th Century neurologist became enshrined in the thinking of modern neuropsychiatry. It looks at how the diagnosis of hysteria and conversion disorder was revitalised by a group of like-minded physicians under the terms of "functional weakness" and "functional neurological deficit" in order to "develop constructive ways of talking with patients". Overton claims this approach has fundamentally failed and the often hilarious jibes he makes at some sectors of the medical profession only highlight further the need for doctors to listen to their patients. "Deserves to be part of the literary canon"-"


Jodi Bassett:

"Simon Overton is a fellow advocate that I communicate with regularly.

Simon was kind enough to ask me to write the forward for this book.

An excerpt from the forward text:

"Substantial medical evidence spanning many decades continues to be ignored by those in positions of power who are abusing that power to further their own vested interests. Once an idea takes root in the scientific community it is not reason but the ability to gather kudos and grab research funding that informs dominant thinking. These groups and individuals are helped immeasurably by the creation of bogus disease categories, categories such as 'Chronic Fatigue Syndrome' and other unscientific concepts such as somatisation disorder, functional weakness, conversion disorder, hysteria, and so on.

Despite an utter lack of scientific legitimacy and the enormous costs to the many patients involved and to the community at large, these massive medical frauds have continued in perpetuity almost entirely unchallenged by the world's media, human rights groups, and governments. It is a worldwide disgrace and one of the biggest scandals in the history of medicine.

How much more extreme do the suffering and abuse caused by these malign scams have to be? How many more very ill patients have to be denied even basic medical care? How many more hundreds of thousands of children and adults worldwide have to be left severely disabled or dead through inappropriate treatment?

Simon Overton is to be congratulated for creating such a timely, intelligent and compelling book on this important topic. More uncompromising educational efforts like this one must be produced if change is ever to occur. The fox has been left in charge of the hen house for far too long already. Knowledge is power.

May the day soon come when such books (and other advocacy projects) are no longer needed, and when patients can rely on something as simple as treatment based on legitimate scientific evidence and on the reality of their pathology - rather than being subjected to various self-serving and illogical pseudo-scientific `theories'. Such ideas are extremely unlikely to help any of the patient groups involved to regain their health."

I highly recommend this book. The chapter which deals with the case of Ean Proctor in particular is a must-read for anyone involved in this field of medicine.

Jodi Bassett, founder of the 'Hummingbirds' Foundation for Myalgic Encephalomyelitis' (HFME)"

ORDER via Amazon

Thursday, June 25, 2009

cognitive dysfunction in CFS/ME ...

Chief Medical Officer’s Report (2003):

“Magnetic resonance imaging studies have found subtle white matter abnormalities in some individuals, more common in those without coexistent psychiatric conditions, leading to the hypothesis that some CFS/ME patients have a subtle encephalopathy.

The numerous studies on cognitive functioning have not always found consistent results and can be criticised for not reflecting the severity of subjective complaints.

However, it seems likely that cognitive dysfunction in CFS/ME cannot be explained solely by the presence of a coexistent psychiatric disorder. Vestibular dysfunction is proposed to explain the widely reported symptom of “dysequilibrium”.“

A gene signature for post-infectious chronic fatigue syndrome

The ME Association is delighted to announce that a provisional abstract and paper on research into gene expression, funded by our Ramsay Research Fund, has today been published by BMC Medical Genomics.

Read more...

Sunday, June 21, 2009

"Anyone who has a classic car hates his wife ... "

Volvo 1800E
"Classic cars are all rubbish. My Mercedes Grosser is rubbish. The Ferrari 250 GTO is rubbish. Even a Lancia Stratos is rubbish. They are typewriters in a computerised world. So why would anyone choose to buy such a thing?

Simple. Anyone who has a classic car hates his wife ....."



Lancia Stratos

Saturday, June 20, 2009

Professor Luc Montagnier and ME


"Scientists have already uncovered a lot about ME, but this information does not reach professional healthcare personnel, and the disease is still not taken seriously.

It is about time this changes."

SOURCE: http://www.hetalternatief.org/Aktueel.htm

Dr. Montagnier is best known for his 1983 discovery of the human immunodeficiency virus (HIV), which has been identified as the cause of AIDS. This discovery led directly to the development of a test for detecting the presence of HIV in blood samples.

Telephone interview with Luc Montagnier immediately following the announcement of the 2008 Nobel Prize in Physiology or Medicine, 6 October 2008. The interview was recorded while Luc Montagnier was attending a conference in the Ivory Coast, and the interviewer is Adam Smith, Editor-in-Chief of Nobelprize.org.

Monday, June 15, 2009

Future hope for ME sufferers?



Despite affecting up o 240,000 people in this country, the true nature of M.E. has eluded scientists. A group's been set up to examine the condition and try to work out a prevention - there are claims that a cure may be near.

Thursday, June 11, 2009

Wednesday, June 10, 2009

Lady GaGa and Speedy !!!


The Poker Face star is taking a break with her boyfriend, known only as Speedy, in Hawaii......

The spy who started the Cold War


MI5 and KGB files have at last revealed the identity of the agent who passed Britain’s atomic bomb secrets to the Soviet Union — and triggered the Cold War

BY Ben Macintyre, The Times

For ten years a Soviet spy codenamed “Eric” fed Britain’s nuclear secrets to Moscow, paving the way for the Cold War. The KGB treasured him as its “main source” of atomic intelligence; MI5 suspected him, trailed him, opened his letters and monitored his every move. But he was never caught.

Today, 70 years later, with the opening of MI5 and KGB files, “Eric” can finally be identified as Engelbert (Bertie) Broda, a brilliant Austrian scientist who evaded Britain’s spy-catchers for a decade while working as a Soviet mole in the heart of the wartime nuclear research programme.

The amazing story of Bertie Broda reads like a John le Carré novel: it is a tale of espionage and counter-espionage, elaborate spycraft, love and deception. But, above all, it is the story of a double-life, filling in one of the last pieces in the complex jigsaw of Cold War espionage.

Broda was the KGB’s prize spy: from the Cavendish Laboratories at the University of Cambridge, he provided Soviet spy chiefs with a stream of Britain’s nuclear secrets, including the blueprint for the early nuclear reactor used in the US Manhattan Project.

Agent “Eric’s” secrets enabled the Soviet Union to catch up in the race to build the bomb and set the stage for the nuclear standoff that followed. The most remarkable thing about the scientist-spy was his ability to evade detection: he died in 1983, a celebrated professor of science at the University of Vienna.

Tuesday, June 9, 2009

Hydrogen sulfide and mitochondria

FASEB J. 2007 Jun;21(8):1699-706. Epub 2007 Feb 21..

Sulfide, the first inorganic substrate for human cells.

Goubern M, Andriamihaja M, Nübel T, Blachier F, Bouillaud F.
Ecole Pratique des Hautes Etudes and Nurélice
UR909, INRA, F-78352 Jouy en Josas, France.

Hydrogen sulfide (H2S) is produced inside the intestine and is known as a poison that inhibits cellular respiration at the level of cytochrome oxidase.

However, sulfide is used as an energetic substrate by many photo- and chemoautotrophic bacteria and by animals such as the lugworm Arenicola marina.

The concentrations of sulfide present in their habitats are comparable with those present in the
human colon.

Using permeabilized colonic cells to which sulfide was added by an infusion pump we show that the maximal respiratory rate of colonocyte mitochondria in presence of sulfide compares with that obtained with succinate or L-alpha-glycerophosphate.
This oxidation is accompanied by mitochondrial energization.

In contrast, other cell types not naturally exposed to high concentration of sulfide showed much lower oxidation rates.

Mitochondria showed a very high affinity for sulfide that permits its use as an energetic substrate at low micromolar concentrations, hence, below the toxic level.

However, if the supply of sulfide exceeds the oxidation rate, poisoning renders mitochondria inefficient and our data suggest that an anaerobic mechanism involving partial reversion of Krebs cycle already known in invertebrates takes place.

In conclusion, this work provides additional and compelling evidence that sulfide is not only a toxic compound. According to our study, sulfide appears to be the first inorganic substrate for mammalian cells characterized thus far.


PMID: 17314140 [PubMed - indexed for MEDLINE]

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