NIH State of the Knowledge Workshop
DAY 1 – THURSDAY, APRIL 7
7:00 - 8:00 a.m. REGISTRATION
8:00 – 8:05 a.m. WELCOME
James M. Anderson, M.D., Ph.D., Division of Program Coordination, Planning and Strategic Initiatives, National Institutes of Health (NIH)
8:05 – 8:15 a.m. OPENING REMARKS
Dennis Mangan, Ph.D., Office of Research on Women’s Health, NIH
PLENARY OVERVIEW
8:15 – 8:45 a.m. Anthony L. Komaroff, M.D., Harvard Medical School
The Clinical Presentation of Chronic Fatigue Syndrome
8:45 – 9:15 a.m. Leonard A. Jason, Ph.D., DePaul University
A Focus on Diagnostic Criteria and Case Definitions
INFECTIOUS DISEASES
NIH Moderator: Catherine Laughlin, Ph.D., National Institute of Allergy and Infectious Diseases, NIH
Co-Moderator: Harvey J. Alter, M.D., Department of Transfusion Medicine, Clinical Center, NIH
9:15 – 9:20 a.m. Session Overview
9:20 – 9:40 a.m. Ronald Glaser, Ph.D., The Ohio State University
Chronic Fatigue Syndrome and the Pathophysiologyof EBV Infection: Trying to Connect the Dots to Make Sense
9:40 – 10:00 a.m. John Chia, M.D., EVMED Research
The Pathogenic Role of Enteroviruses in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
10:00 – 10:15 a.m. MORNING BREAK
10:15 – 10:35 a.m. Judy A. Mikovits, Ph.D., Whittemore Peterson Institute
XMRV and MLV-Related Viruses in Chronic Fatigue Syndrome
10:35 – 10:55 a.m. John M. Coffin, Ph.D., National Cancer Institute, NIH
Endogenous Retroviral Origin of XMRV and MLV-like Sequences
10:55 – 11:15 a.m. Summary and Panel Discussion
SYSTEMS BIOLOGY
NIH Moderator: Basil Eldadah, M.D., Ph.D., National Institute on Aging, NIH
Co-Moderator: TBN
11:15 – 11:20 a.m. Session Overview
11:20 – 11:40 a.m. Gordon Broderick, Ph.D., University of Alberta
Regulatory Imbalance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Network Biology Perspective
11:40 a.m. – 12:00 p.m. Mangalathu Rajeevan, Ph.D., Centers for Disease Control and Prevention
Genomic Studies of Chronic Fatigue Syndrome
12:00 – 12:20 p.m. Keith W. Kelley, Ph.D., University of Illinois at Urbana-Champaign
From Systemic Infection to Brain Inflammation
12:20 – 12:35 p.m. Summary and Panel Discussion
12:35 – 1:30 p.m. LUNCH
IMMUNOLOGY
NIH Moderator: Timothy A. Gondré -Lewis, Ph.D., National Institute of Allergy and Infectious Diseases, NIH
Co-Moderator: David M. Mosser, Ph.D., University of Maryland
1:30 – 1:35 p.m. Session Overview
1:35 – 1:55 p.m. Mary Ann Fletcher, Ph.D., University of Miami, Miller School of Medicine
Immunology of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and GWI
1:55 – 2:15 p.m. Benjamin Natelson, M.D., Albert Einstein College of Medicine
Chronic Fatigue Syndrome and Fibromyalgia Are Not Always the Same
2:15 – 2:30 p.m. Summary and Panel Discussion
2:30 – 2:40 p.m. Francis S. Collins, M.D., Ph.D., Director, National Institutes of Health (NIH)
NEUROLOGY
NIH Moderator: John Kusiak, Ph.D., National Institute of Dental and Craniofacial Research, NIH
Co-Moderator: Shaheen Lakhan, M.D., Ph.D., M.S., M.Ed., Global Neuroscience Initiative Foundation
2:40 – 2:45 p.m. Session Overview
2:45 – 3:05 p.m. Kathleen C. Light, Ph.D., University of Utah
Greater Post-Exercise Gene Expression of Adrenergic and Sensory Receptors and Cytokines in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome versus Multiple Sclerosis, Fibromyalgia, and Healthy Controls
3:05 – 3:20 p.m. AFTERNOON BREAK
3:20 – 3:40 p.m. Roy Freeman, M.D., Beth Israel Deaconess Medical Center, Harvard Medical School
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Autonomic Nervous System
3:40 – 4:00 p.m. James Baraniuk, M.D., Georgetown University
Neuroimmunology of Chronic Fatigue Syndrome
4:00 – 4:15 p.m. Summary and Panel Discussion
EXERCISE PHYSIOLOGY AND ENERGY METABOLISM
NIH Moderator: Cheryl L. McDonald, M.D., National Heart, Lung, and Blood Institute, NIH
Co-Moderator: Kevin P. Davy, Ph.D., Virginia Polytechnic Institute and State University
4:15 – 4:20 p.m. Session Overview
4:20 – 4:40 p.m. Jane Kent-Braun, Ph.D., University of Massachusetts, Amherst
Muscle Function and Fatigue in Chronic Fatigue Syndrome
4:40 – 5:00 p.m. Christopher R. Snell, Ph.D., University of the Pacific/Pacific Fatigue Lab, Stockton, CA Cardiopulmonary Exercise Testing and the Assessment of Fatigue in CFS/ME
5:00 – 5:20 p.m. Peter C. Rowe, M.D., Johns Hopkins University School of Medicine
Orthostatic Intolerance in Chronic Fatigue Syndrome
5:20 – 5:45 p.m. Summary and Panel Discussion
DAY 2 – FRIDAY, APRIL 8
7:00 – 8:00 a.m. REGISTRATION
8:00 – 8:15 a.m. RECONVENE
DIAGNOSIS AND BIOMARKERS
NIH Moderator: Donald G. Blair, Ph.D., National Cancer Institute, NIH
Co-Moderator: Samir Khleif, M.D., National Cancer Institute, NIH
8:15 – 8:35 a.m. Nancy Klimas, M.D., University of Miami, Miller School of Medicine
Immune Based Biomarkers in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
8:35 – 8:55 a.m. Dane B. Cook, Ph.D., University of Wisconsin, Madison
Can Functional Neuroimaging Data Serve as a Biomarker for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?
8:55 – 9:15 a.m. Michael Dean, Ph.D., National Cancer Institute, NIH
Identifying Genes and Genetic Risk Factors for Complex Diseases
9:15 – 9:35 a.m. Summary and Panel Discussion
TREATMENT
NIH Moderator: Christopher Mullins, Ph.D., National Institute of Diabetes and Digestive and Kidney Diseases, NIH
Co-Moderator: Susan Keay, M.D., Ph.D., University of Maryland School of Medicine; and Veterans Administration Maryland Health Care System
9:35 – 9:40 a.m. Session Overview
9:40 – 10:00 a.m. Fred Friedberg, Ph.D., State University of New York, Stony Brook
Self-Management in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Meaning of "Improvement"
10:00 – 10:20 a.m. Italo Biaggioni, M.D., Vanderbilt University
Chronic Fatigue and Postural Tachycardia Syndromes
10:20 – 10:35 a.m. MORNING BREAK
10:35 – 10:55 a.m. Theoharis C. Theoharides, M.D., Ph.D., M.S., F.A.A.A.A.I., Tufts University School of Medicine Substance P-Stimulated TNF Secretion from Human Mast Cells Involves Fission and Translocation of Mitochondria with Extracellular DNA Release That Induces Auto-Inflammation, Processes Blocked by the Natural Flavonoid Luteolin
10:55 – 11:15 a.m. Lucinda Bateman, M.D., Fatigue Consultation Clinic, Salt Lake City
Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome at the Fatigue Consultation Clinic: The Art of Supportive Care Medicine
11:15 – 11:45 a.m. Summary and Panel Discussion
11:45 a.m. – 1:00 p.m. LUNCH
OPPORTUNITIES FOR COMMUNICATION (A Panel Discussion)
NIH Moderators: John T. Burklow and Marin P. Allen, Ph.D., Office of Communications and Public Liaison, NIH
1:00 – 1:05 p.m. Session Overview
1:05 – 1:15 p.m. K. Kimberly McCleary, CFIDS Association of America
Communicating with Research Stakeholders
1:15 – 1:25 p.m. Kenneth J. Friedman, Ph.D., Castleton State College
Elephants in the Room: Acknowledging Impediments to Chronic Fatigue Syndrome Research and Education
1:25 – 1:40 p.m. Patricia Fero, M.E.P.D., Wisconsin ME/CFS Association, Inc.
3 Generations: A View from Wisconsin
Mary M. Schweitzer, Ph.D., MCEAS, University of Pennsylvania
The Role for Internet in Communication
1:40 – 1:50 p.m. John T. Burklow, Office of Communications and Public Liaison, NIH
1:50 – 2:15 p.m. Summary and Panel Discussion
2:15 – 2:30 p.m. AFTERNOON BREAK
SUMMARY
NIH Moderator: Dennis Mangan, Ph.D., Office of Research on Women's Health, NIH
Co-Moderator: Suzanne D. Vernon, Ph.D., CFIDS Association of America
2:30 – 4:45 p.m. All Speakers and Co-Moderators
• Summary of Each Session
• Responses by Department of Health and Human Services Federal Agencies
• Full Workshop Panel Discussion
4:45 – 5:00 p.m. CLOSING COMMENTS
Vivian W. Pinn, M.D., Office of Research on Women's Health, NIH
Sponsored by
The Office of Research on Women's Health,
National Institutes of Health (NIH)
In collaboration with
The Trans-NIH ME/CFS Research Working Group
If you have any questions, call (703) 925-9455 ext. 0 or e-mail icg@infinityconferences.com
LIVE Webcast HERE
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