Monday, April 18, 2011

This is huge: Post-exertional malaise, the hallmark symptom of ME/CFS, can be reliably measured

CFS Patient Advocate:

two researchers, Dr. Light and Dr. Snell, presented important data about post-exertional malaise, coming at the problem from very different angles. Dr. Snell’s presentation was in Exercise Physiology and Metabolism (there were, by the way, no other presentations on metabolism in this session, despite an abundance of research on oxidative stress in ME/CFS);

Dr. Light’s presentation was in Neurology, for reasons that are unclear--adrenergic gene expression upregulation? Well, yes, but just as importantly inflammatory cytokine gene expression upregulation and acid-sensing ion channels gene expression upregulation.

This presentation could as easily have been put in immunology or metabolism. But they both really belonged in a separate session called Biomarkers for Post-Exertional Malaise (or effort-induced exacerbation, a better name). This would help patients.

Post-exertional malaise is considered by many to be the hallmark symptom of this disease.

These two researchers say it can be reliably measured.

That means it may be able to be understood and be treated. Or used to follow the response to treatment of other aspects of the disease. This is huge. Read more>>

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