Friday, October 7, 2011

Mechanisms of Mitochondrial Defects in Gulf War Syndrome
This study is currently recruiting participants.
Verified on September 2011 by Medical Neurogenetics, LLC

First Received on December 17, 2010.   Last Updated on September 20, 2011   History of Changes
Sponsor:Medical Neurogenetics, LLC
Collaborator:Department of Defense
Information provided by (Responsible Party):John M. Shoffner, Medical Neurogenetics, LLC Identifier:NCT01264471
The purpose of the study is to investigate possible causes for Gulf War SyndromeGulf War Syndrome is associated with increased incidences of amyotrophic lateral sclerosis (Lou Gehrig's Disease), pain syndromes, muscle complaints that include fatigue and myalgias (muscle pain), as well as other neurological symptoms. Abnormalities in the part of the cell known as mitochondria have been delineated in Gulf War Syndrome. Mitochondria are the "power plants" of the body. Mitochondria take the food you eat and break the food down into a form of energy that the body can use. The investigators propose that Gulf War Syndrome is determined by a complex interaction of factors that interfere with mitochondrial function. This study will be the first investigation of mitochondrial function inGulf War Syndrome. The investigators objective is to establish the cause for symptoms in affected veterans, develop testing that can more easily identify Gulf War Syndrome, and ultimately develop treatment protocols for Gulf War Syndrome.

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