By Professor Art Ayers:
CFS/ME results in increased levels of the receptors for IL-6 and TNF, but not for the corresponding cytokines, IL-6 and TNF, which trigger fatigue and wasting associated with chronic inflammatory diseases. These findings suggest that people with CFS/ME should be very sensitive to activities or conditions that produce inflammatory cytokines
People with CFS/ME do not seem to benefit from exercise, but rather the combination of exercise-induced IL-6, together with enhanced preexisting IL-6 receptors, produces extreme fatigue.
Many doctors discourage CFS/ME sufferers from exercising, because the exercise-based IL-6 never reaches therapeutic levels required for muscle enhancement.
These recent studies explain what people with CFS/ME have experienced -- exercise is bad for CFS/ME. Hopefully, therapy will follow the new insights. Read more>>
See also: Professor Paul Cheney: why exercise in CFS is counter-productive