Monday, August 29, 2016

ME/CFS has an objectively identifiable chemical signature in both men and women 

ME/CFS has an objectively identifiable chemical signature in both men and women 

  By: Robert K. Naviaux a ,b ,c ,d ,1 , * Jane C. Naviaux a ,e , * Kefeng Li a ,b , * A. Taylor Bright a ,b , * William A. Alaynick a ,b , * Lin Wang a ,b , * Asha Baxter f , * Neil Nathan f ,2 , * Wayne Anderson f , and * Eric Gordon

  "Patients with CFS showed abnormalities in 20 metabolic pathways. Eighty percent of the diagnostic metabolites were decreased, consistent with a hypometabolic syndrome."

"We studied a total of 84 subjects using these methods. Forty-five subjects (n = 22 men and 23 women) met diagnostic criteria for ME/CFS by Institute of Medicine, Canadian, and Fukuda criteria. Thirty-nine subjects (n = 18 men and 21 women) were age- and sex-matched normal controls. Males with CFS were 53 (±2.8) y old (mean ± SEM; range, 21–67 y). Females were 52 (±2.5) y old (range, 20–67 y). The Karnofsky performance scores were 62 (±3.2) for males and 54 (±3.3) for females."

1 comment:

Hope said...

Thanks for the link to this article.
The finding of "hypometabolic response to environmental stress" in patients who met the diagnostic criteria of CFS used, namely chronic fatigue of unknown origin, (Fukuda 1994, Carruthers 2003, IOM 2015), is irrelevant to patients and doctors working with patients who have ME a disease of acquired CNS dysfunction( Ramsey, Hyde 2006, see ).
It is criminally negligent for professional medical scientists to publish "CFS/ME" as a diagnosis, when the WHO has made it clear that they are distinct diseases. Unfortunately, there are many rewards and no punishments for this misrepresentation.
Meanwhile, many with ME live difficult and pain-filled lives with a misrepresented disease, and on average die 25 years earlier than expected.


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