Thursday, February 24, 2011

The PACE Trial aka the trial with serious conflicts of interest used no objective measures of outcome

Pace Trial: the facts at a glance:


“at best, PACE is telling us that the two main therapies currently recommended by the National Institute for Health and Clinical Excellence (NICE) are only moderately effective.” Action for ME

“The results of the PACE Trial may mean that patients who have genuine ME as opposed to chronic “fatigue” will continue to be denied appropriate investigation and treatment; they may be deprived of State benefits necessary for survival; their insurance claims may be rejected, and they will be condemned to an even lower quality of life.” Professor Malcolm Hooper

The PACE Trial was funded by the U.K. Medical Research Council, the U.K. Department of Health and the U.K. Department for Work and Pensions.

5. There is a concern of serious conflicts of interest at the UK Department of Work and Pensions (DWP) who part-funded the PACE Trial. Like the permanent health insurance industry, the DWP has a potential financial vested interest if patients' disability can be portrayed as caused by or largely exacerbated by behavioural factors.

6.The patient population was selected using the Oxford criteria for CFS. 3,148 patients diagnosed with CFS recruited from six CFS speciality clinics were screened to identify 641subjects who met study criteria.

7.The MRC PACE Trial excluded children and those who are severely affected. The results of any trial that excluded those who are severely affected cannot be taken seriously.

8.The PACE Trial used no objective measures of outcome ... Read more>>

No comments:


Related Posts with Thumbnails