Tuesday, June 7, 2011

XMRV-related abstracts from 15th International Conference on Human Retroviruses

Jamie Deckoff-Jones MD:

For easier reading and sharing XMRV Global Action has compiled the XMRV related abstracts from the 15th International Conference on Human Retroviruses: HTLV and Related Viruses, Leuven and Gembloux, Belgium. 5-8 June 2011

1. XMRV replicates preferentially in mucosal sites in vivo: Relevance to XMRV transmission?


Francois Villinger1,2*, Jaydip Das Gupta3, Nattawat Onlamoon4, Ross Molinaro1,2, Suganthi Suppiah1,2, Prachi Sharma5, Kenneth Rogers5, Christina Gaughan3, Eric Klein3, Xiaoxing Qiu6, Gerald Schochetman6, John Hackett Jr6, Robert H Silverman3

"In fact, a single atraumatic mucosal exposure with a high dose of XMRV virus into the urethra resulted in infection of 1 out of 4 macaques providing proof of concept that such transmission is possible. However, additional work is needed to fully investigate potential modes of XMRV infection."
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