Tuesday, March 1, 2011

Genetic and Genomic markers of CFS risk, progression and prognosis

Alan R. Light, University of Utah, Departments of Anesthesiology and Neurobiology and Anatomy, CFSAC Day, Oct. 12th 2010:

88 genes differentially associated with CFS, and subgroup associations with specific viruses were found in CFS patients by the group headed by J.R. Kerr.

We postulate that this “sensory” fatigue comes in several flavors—two common ones,

• 1) The perception of tiredness, heaviness, pressure, “lead leggedness” that accompanies prolonged muscle contraction—this is felt before the ache and burn we feel with sustained contraction

• 2) The perception of lack of focus, confusion, ‘tiredness’ that accompanies exhausting mental tasks, other wise known as ‘mental fatigue’
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See also: Metabolic dysfunction causes Post-Exertional malaise in ME/CFS

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